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Human HMGB1 Recombinant Protein Mouse IgG Fc Tag Lyophilized

Human HMGB1 Recombinant Protein Mouse IgG Fc Tag Lyophilized

$ 48.88

$ 63.54

Unavailable
Human HMGB1 Recombinant Protein Mouse IgG Fc Tag Lyophilized

Human HMGB1 Recombinant Protein Mouse IgG Fc Tag Lyophilized

$ 48.88

$ 63.54

Volume:
  • 100UG
Unavailable
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Product Details

Human HMGB1 Recombinant Protein Mouse IgG Fc Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 cells. This is a Lyophilized protein buffered in Tris with Glycine, Arginine and NaCl, pH7.5 with a purity of >95% as determined by SDS-PAGE..

More Details:

  • Species: Human
  • Target: HMGB1
  • Purity: >95% as determined by SDS-PAGE.
  • Source: HEK293 cells
  • Storage Conditions: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Additional Information:
High-mobility group protein B1 (HMGB1) is also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 is a non-histone architectural chromosomal protein ubiquitously present in all vertebrate nuclei and binds double-stranded DNA without sequence specificity. The mechanism of inflammation and damage is binding to TLR4, which mediates HMGB1-dependent activation of macrophage cytokine release. This positions HMGB1 at the intersection of sterile and infectious inflammatory responses. HMGB1 has been studied as a DNA vaccine adjuvant and a target for cancer therapy.

This protein carries a mouse IgG2a Fc Tag at the N-terminal. The protein has a calculated MW of 51.6 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.

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